Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 12/20 | 0.64 |
| ▸ | MET | P08581 | 5/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487734 | 1.00 | MAP4K4 (0.64) | MAP4K4METNR4A2JAK2FEN1 | |
| SCHEMBL30454350 | 0.90 | MAP4K4 (0.65) | MAP4K4METNR4A2 | |
| SCHEMBL487663 | 0.90 | MAP4K4 (0.65) | MAP4K4METNR4A2 | |
| SCHEMBL30453255 | 0.88 | MET (0.65) | MAP4K4METJAK2 | |
| SCHEMBL487782 | 0.88 | MET (0.65) | MAP4K4METJAK2 | |
| SCHEMBL30454971 | 0.87 | MAP4K4 (0.73) | MAP4K4METNR4A2 | |
| SCHEMBL487832 | 0.87 | MAP4K4 (0.73) | MAP4K4METNR4A2 | |
| SCHEMBL487833 | 0.86 | JAK2 (0.58) | MAP4K4METJAK2 | |
| SCHEMBL30453620 | 0.83 | MET (0.55) | MAP4K4MET | |
| SCHEMBL30452936 | 0.83 | MET (0.55) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |