Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 7/20 | 0.65 |
| ▸ | MET | P08581 | 3/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.50 |
| ▸ | INPPL1 | O15357 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487663 | 1.00 | MAP4K4 (0.65) | MAP4K4METNR4A2NR4A1NR4A3 | |
| SCHEMBL30452968 | 0.90 | MAP4K4 (0.64) | MAP4K4METNR4A2 | |
| SCHEMBL487734 | 0.90 | MAP4K4 (0.64) | MAP4K4METNR4A2 | |
| SCHEMBL30454971 | 0.88 | MAP4K4 (0.73) | MAP4K4METNR4A2HDAC8 | |
| SCHEMBL487832 | 0.88 | MAP4K4 (0.73) | MAP4K4METNR4A2HDAC8 | |
| SCHEMBL487769 | 0.87 | MET (0.66) | MAP4K4METINPPL1 | |
| SCHEMBL30453337 | 0.87 | MET (0.66) | MAP4K4METINPPL1 | |
| SCHEMBL30453352 | 0.82 | MET (0.64) | MAP4K4MET | |
| SCHEMBL487655 | 0.82 | MET (0.64) | MAP4K4MET | |
| SCHEMBL30453900 | 0.82 | MET (0.64) | MAP4K4MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |