Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.65 |
| ▸ | USP7 | Q93009 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 3/20 | 0.46 |
| ▸ | FYN | P06241 | 5/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487782 | 1.00 | MET (0.65) | METUSP7JAK2FYNMAP4K4 | |
| SCHEMBL30453337 | 0.89 | MET (0.66) | METUSP7FYNMAP4K4MAP4K3 | |
| SCHEMBL487833 | 0.89 | JAK2 (0.58) | METJAK2FYNMAP4K4MAP4K3 | |
| SCHEMBL487769 | 0.89 | MET (0.66) | METUSP7FYNMAP4K4MAP4K3 | |
| SCHEMBL30452968 | 0.88 | MAP4K4 (0.64) | METJAK2MAP4K4 | |
| SCHEMBL487734 | 0.88 | MAP4K4 (0.64) | METJAK2MAP4K4 | |
| SCHEMBL27630151 | 0.86 | MET (0.48) | METJAK2FYNMAP4K4MAP4K3 | |
| SCHEMBL487657 | 0.85 | MET (0.75) | METUSP7FYNMAP4K4MAP4K3 | |
| SCHEMBL30452824 | 0.85 | MET (0.75) | METUSP7FYNMAP4K4MAP4K3 | |
| SCHEMBL27630242 | 0.85 | MET (0.75) | METUSP7FYNMAP4K4MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |