SCHEMBL30452996

SCHEMBL30452996

O=C1CCc2ccccc2N1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.56
AADAT Q8N5Z0 2/20 0.49
GOT1 P17174 1/20 0.49
KYAT1 Q16773 1/20 0.49
KYAT3 Q6YP21 1/20 0.49
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B3 P37058 1/20 0.46
NPC1 O15118 1/20 0.46
MITF O75030 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
RNASEH1 O60930 1/20 0.44
CYP2A6 P11509 1/20 0.43
SRD5A1 P18405 1/20 0.43
OPRM1 P35372 1/20 0.43
OPRK1 P41145 1/20 0.43
OPRL1 P41146 1/20 0.43
NOTUM Q6P988 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2142614 1.00 POLB (0.56) POLBAADATGOT1KYAT1KYAT3
SCHEMBL13826481 0.84 MEN1 (0.48) POLBAADATGOT1KYAT1KYAT3
SCHEMBL29836002 0.81 RNASEH1 (0.60) POLBAADATGOT1KYAT1KYAT3
SCHEMBL3195836 0.81 RNASEH1 (0.60) POLBAADATGOT1KYAT1KYAT3
SCHEMBL29733604 0.75 POLB (0.51) POLBMEN1KMT2AHSD17B3NPC1
SCHEMBL1396793 0.75 POLB (0.51) POLBMEN1KMT2AHSD17B3NPC1
SCHEMBL3389475 0.75 POLB (0.51) POLBMEN1KMT2AHSD17B3NPC1
SCHEMBL761220 0.75 SRD5A1 (0.54) POLBMEN1KMT2AHSD17B3SMN1; SMN2
SCHEMBL30100746 0.75 POLB (0.51) POLBMEN1KMT2AHSD17B3NPC1
SCHEMBL11404877 0.75 POLB (0.56) POLBMEN1KMT2AHSD17B3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025229046-A1 SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME MOLIUS SAGLIK TEKNOLOJILERI ANONIM SIRKETI (TR) 2025-11-06 WO disclosed
EP-4644375-A1 SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME Molius Saglik Teknolojileri Anonim Sirketi (TR) 2025-11-05 EP disclosed
CN-116249533-A Intestinal tract cracking type co-drug and preparation and application thereof 轶诺(浙江)药业有限公司 2023-06-09 CN disclosed