Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640 | 0.85 | FFAR1 (0.45) | LMNASLC2A1ALDH1A1HPGDKDM4E | |
| SCHEMBL3721962 | 0.76 | ALDH1A1 (0.47) | LMNAALDH1A1HPGDKDM4EERN1 | |
| SCHEMBL13265071 | 0.76 | ALDH1A1 (0.47) | LMNAALDH1A1HPGDKDM4EERN1 | |
| SCHEMBL15145284 | 0.75 | LMNA (0.59) | LMNAALDH1A1HPGDKDM4EERN1 | |
| SCHEMBL2505577 | 0.73 | HDAC8 (0.50) | LMNAALDH1A1HPGDKDM4EERN1 | |
| SCHEMBL20505239 | 0.71 | LMNA (0.59) | LMNAALDH1A1HPGDKDM4EERN1 | |
| SCHEMBL289027 | 0.71 | LMNA (0.59) | LMNAALDH1A1HPGDKDM4EERN1 | |
| SCHEMBL18811323 | 0.71 | NQO1 (0.48) | LMNAALDH1A1HPGDKDM4EDHFR | |
| SCHEMBL1125718 | 0.70 | ALDH1A1 (0.55) | LMNAALDH1A1KDM4EERN1HSD17B10 | |
| SCHEMBL9498221 | 0.70 | NQO1 (0.46) | LMNAALDH1A1HPGDKDM4EERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |