Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 6/20 | 0.50 |
| ▸ | MET | P08581 | 3/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488513 | 1.00 | ATR (0.50) | ATRMETCSF1RMAPTALDH1A1 | |
| SCHEMBL487751 | 0.95 | ATR (0.55) | ATRMETCSF1RALDH1A1 | |
| SCHEMBL30453304 | 0.95 | ATR (0.55) | ATRMETCSF1RALDH1A1 | |
| SCHEMBL30454451 | 0.93 | KLK7 (0.47) | METALDH1A1MEN1KMT2A | |
| SCHEMBL488475 | 0.93 | KLK7 (0.47) | METALDH1A1MEN1KMT2A | |
| SCHEMBL488105 | 0.92 | ATR (0.53) | ATRMETCSF1RMAPTMEN1 | |
| SCHEMBL30453359 | 0.92 | ATR (0.53) | ATRMETCSF1RMAPTMEN1 | |
| SCHEMBL489831 | 0.91 | MET (0.43) | ATRMETMAPTALDH1A1THRB | |
| SCHEMBL488479 | 0.88 | CD274 (0.50) | ATRMETALDH1A1 | |
| SCHEMBL30453023 | 0.88 | CD274 (0.50) | ATRMETALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |