Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MET | P08581 | 4/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | MTOR | P42345 | 4/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 2/20 | 0.36 |
| ▸ | IKBKG | Q9Y6K9 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488785 | 1.00 | L3MBTL3 (0.45) | L3MBTL3L3MBTL1METCSF1RACKR3 | |
| SCHEMBL30453950 | 0.86 | KDM4E (0.40) | METCSF1RATRMTORHRH3 | |
| SCHEMBL488731 | 0.86 | KDM4E (0.40) | METCSF1RATRMTORHRH3 | |
| SCHEMBL488190 | 0.86 | MET (0.54) | L3MBTL3L3MBTL1METCSF1RATR | |
| SCHEMBL30453638 | 0.86 | MET (0.54) | L3MBTL3L3MBTL1METCSF1RATR | |
| SCHEMBL30452767 | 0.85 | MET (0.54) | L3MBTL3L3MBTL1METPIK3CAMTOR | |
| SCHEMBL487710 | 0.85 | MET (0.54) | L3MBTL3L3MBTL1METPIK3CAMTOR | |
| SCHEMBL488097 | 0.84 | ATR (0.56) | L3MBTL3L3MBTL1METCSF1RATR | |
| SCHEMBL30453351 | 0.84 | ATR (0.56) | L3MBTL3L3MBTL1METCSF1RATR | |
| SCHEMBL488332 | 0.83 | MET (0.60) | METCSF1RATRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |