Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 8/20 | 0.40 |
| ▸ | CSF1R | P07333 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | MAP3K1 | Q13233 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488731 | 1.00 | KDM4E (0.40) | KDM4ENPC1ALDH1A1RAB9AMET | |
| SCHEMBL5490531 | 0.86 | KDM4E (0.40) | KDM4ENPC1ALDH1A1RAB9AMET | |
| SCHEMBL488785 | 0.86 | L3MBTL3 (0.45) | METCSF1RHRH3MTORATR | |
| SCHEMBL30453033 | 0.86 | L3MBTL3 (0.45) | METCSF1RHRH3MTORATR | |
| SCHEMBL30453871 | 0.86 | MET (0.42) | METCSF1RMTOR | |
| SCHEMBL488396 | 0.86 | MET (0.42) | METCSF1RMTOR | |
| SCHEMBL30453528 | 0.84 | KCNH2 (0.53) | METCSF1RAURKAAURKBKCNH2 | |
| SCHEMBL488017 | 0.84 | KCNH2 (0.53) | METCSF1RAURKAAURKBKCNH2 | |
| SCHEMBL487709 | 0.84 | MET (0.49) | KDM4ENPC1ALDH1A1RAB9AMET | |
| SCHEMBL30454688 | 0.84 | MET (0.49) | KDM4ENPC1ALDH1A1RAB9AMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |