Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.48 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.48 |
| ▸ | INPPL1 | O15357 | 3/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488147 | 1.00 | MET (0.52) | METJAK2MAP4K3MAP4K4CYP1A2 | |
| SCHEMBL3122066 | 0.89 | MET (0.56) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL487679 | 0.86 | MET (0.57) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL488590 | 0.85 | JAK2 (0.51) | METJAK2MAP4K3INPPL1 | |
| SCHEMBL488295 | 0.85 | MET (0.52) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL30452799 | 0.85 | MET (0.52) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL487842 | 0.85 | JAK2 (0.60) | METJAK2MAP4K3 | |
| SCHEMBL30453168 | 0.85 | JAK2 (0.60) | METJAK2MAP4K3 | |
| SCHEMBL28756897 | 0.84 | MET (0.51) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL27630181 | 0.84 | MET (0.51) | METJAK2MAP4K3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |