Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257719 | 1.00 | CYP1A2 (0.39) | CYP1A2KDM4ELMNAPOLBCASP6 | |
| SCHEMBL24257739 | 0.84 | POLB (0.48) | CYP1A2POLB | |
| SCHEMBL30546884 | 0.84 | POLB (0.48) | CYP1A2POLB | |
| SCHEMBL30546851 | 0.83 | DHFR (0.43) | CYP1A2KDM4EPOLB | |
| SCHEMBL24257623 | 0.83 | DHFR (0.43) | CYP1A2KDM4EPOLB | |
| SCHEMBL24257735 | 0.80 | ALOX15 (0.48) | CYP1A2 | |
| SCHEMBL30546870 | 0.80 | KDM4E (0.35) | KDM4EPOLB | |
| SCHEMBL24257763 | 0.80 | KDM4E (0.35) | KDM4EPOLB | |
| SCHEMBL24257718 | 0.77 | SMN1; SMN2 (0.39) | KDM4ELMNAPOLB | |
| SCHEMBL30452995 | 0.77 | SMN1; SMN2 (0.39) | KDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |