Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 4/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488296 | 1.00 | MAP4K3 (0.52) | MAP4K3JAK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30453373 | 0.88 | CYP11B1 (0.63) | MAP4K3JAK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL488124 | 0.88 | CYP11B1 (0.63) | MAP4K3JAK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL488562 | 0.86 | MAP4K3 (0.54) | MAP4K3JAK2MAP4K4METNPC1 | |
| SCHEMBL30454152 | 0.83 | MAP4K4 (0.59) | MAP4K3MAP4K4METLTA4H | |
| SCHEMBL488102 | 0.83 | MAP4K4 (0.59) | MAP4K3MAP4K4METLTA4H | |
| SCHEMBL488667 | 0.82 | MET (0.70) | MAP4K3JAK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30452701 | 0.82 | MET (0.70) | MAP4K3JAK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL488416 | 0.81 | MAP4K3 (0.54) | MAP4K3JAK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30454968 | 0.81 | MAP4K3 (0.54) | MAP4K3JAK2CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |