Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | ATR | Q13535 | 3/20 | 0.46 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488697 | 1.00 | MET (0.55) | METCNR1ATRMAP4K3ADRA2A | |
| SCHEMBL488395 | 0.94 | CNR1 (0.49) | METCNR1MAP4K3EPHX2 | |
| SCHEMBL30453036 | 0.94 | CNR1 (0.49) | METCNR1MAP4K3EPHX2 | |
| SCHEMBL488227 | 0.89 | MET (0.68) | METATRMAP4K3CHEK2 | |
| SCHEMBL30454506 | 0.89 | MET (0.68) | METATRMAP4K3CHEK2 | |
| SCHEMBL30452704 | 0.88 | MET (0.45) | METATRMAP4K3CHEK2 | |
| SCHEMBL488978 | 0.88 | MET (0.45) | METATRMAP4K3CHEK2 | |
| SCHEMBL488931 | 0.87 | MET (0.55) | METCNR1ADRA2AADRA2BKCNH2 | |
| SCHEMBL487919 | 0.86 | MET (0.74) | METCNR1 | |
| SCHEMBL30452751 | 0.86 | MET (0.74) | METCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |