Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488978 | 1.00 | MET (0.45) | METMAP4K3CHEK2PIK3CAPIK3CD | |
| SCHEMBL30454699 | 0.95 | MET (0.51) | METMAP4K3CHEK2 | |
| SCHEMBL488836 | 0.95 | MET (0.51) | METMAP4K3CHEK2 | |
| SCHEMBL30453380 | 0.88 | MET (0.55) | METMAP4K3CHEK2ATR | |
| SCHEMBL488697 | 0.88 | MET (0.55) | METMAP4K3CHEK2ATR | |
| SCHEMBL488027 | 0.86 | MET (0.38) | METAURKA | |
| SCHEMBL30453036 | 0.86 | CNR1 (0.49) | METMAP4K3PIK3CAPIK3CDPIK3CG | |
| SCHEMBL488395 | 0.86 | CNR1 (0.49) | METMAP4K3PIK3CAPIK3CDPIK3CG | |
| SCHEMBL487897 | 0.84 | MET (0.56) | MET | |
| SCHEMBL30454510 | 0.84 | MET (0.56) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |