Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488395 | 1.00 | CNR1 (0.49) | CNR1SMN1; SMN2METLMNAALK | |
| SCHEMBL488697 | 0.94 | MET (0.55) | CNR1METEPHX2MAP4K3 | |
| SCHEMBL30453380 | 0.94 | MET (0.55) | CNR1METEPHX2MAP4K3 | |
| SCHEMBL488600 | 0.90 | MET (0.59) | METALK | |
| SCHEMBL30454107 | 0.90 | MET (0.59) | METALK | |
| SCHEMBL10216403 | 0.89 | MET (0.48) | METALKEPHX2MAP4K3PIK3CA | |
| SCHEMBL30452704 | 0.86 | MET (0.45) | METMAP4K3PIK3CDPIK3CAPIK3CG | |
| SCHEMBL488978 | 0.86 | MET (0.45) | METMAP4K3PIK3CDPIK3CAPIK3CG | |
| SCHEMBL488328 | 0.86 | MET (0.65) | CNR1SMN1; SMN2METLMNAALK | |
| SCHEMBL30452822 | 0.86 | MET (0.65) | CNR1SMN1; SMN2METLMNAALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |