Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.54 |
| ▸ | MET | P08581 | 6/20 | 0.53 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | LDHB | P07195 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488121 | 1.00 | MAP4K4 (0.54) | MAP4K4METIKBKETBK1JAK2 | |
| SCHEMBL5480970 | 0.92 | MET (0.53) | MAP4K4METJAK2MAP4K3 | |
| SCHEMBL30453201 | 0.89 | MAP4K4 (0.64) | MAP4K4METJAK2MAP4K3 | |
| SCHEMBL487982 | 0.89 | MAP4K4 (0.64) | MAP4K4METJAK2MAP4K3 | |
| SCHEMBL30453565 | 0.86 | MET (0.67) | MAP4K4METIKBKETBK1MRGPRX4 | |
| SCHEMBL487900 | 0.86 | MET (0.67) | MAP4K4METIKBKETBK1MRGPRX4 | |
| SCHEMBL487679 | 0.86 | MET (0.57) | MAP4K4METJAK2MAP4K3 | |
| SCHEMBL5480975 | 0.85 | MET (0.53) | MAP4K4METJAK2MAP4K3 | |
| SCHEMBL30453694 | 0.84 | MET (0.54) | MAP4K4MET | |
| SCHEMBL487934 | 0.84 | MET (0.54) | MAP4K4MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |