Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.67 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.57 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | LDHB | P07195 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487900 | 1.00 | MET (0.67) | METMAP4K4IKBKETBK1MEN1 | |
| SCHEMBL30453780 | 0.90 | MET (0.76) | METMAP4K4HPGD | |
| SCHEMBL487674 | 0.90 | MET (0.76) | METMAP4K4HPGD | |
| SCHEMBL30453459 | 0.86 | MAP4K4 (0.54) | METMAP4K4IKBKETBK1LDHA | |
| SCHEMBL488121 | 0.86 | MAP4K4 (0.54) | METMAP4K4IKBKETBK1LDHA | |
| SCHEMBL488515 | 0.86 | MET (0.62) | METMAP4K4MEN1NPC1MITF | |
| SCHEMBL487907 | 0.85 | MET (0.81) | METMAP4K4 | |
| SCHEMBL30454723 | 0.84 | MET (0.79) | METMAP4K4 | |
| SCHEMBL487730 | 0.84 | MET (0.79) | METMAP4K4 | |
| Water SCHEMBL28121971 | 0.84 | MET (0.79) | METMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |