Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.74 |
| ▸ | MET | P08581 | 10/20 | 0.59 |
| ▸ | INPPL1 | O15357 | 6/20 | 0.52 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21478593 | 0.85 | JAK2 (1.00) | JAK2MET | |
| SCHEMBL30142949 | 0.85 | JAK2 (1.00) | JAK2MET | |
| SCHEMBL21478982 | 0.85 | JAK2 (1.00) | JAK2MET | |
| SCHEMBL3391902 | 0.81 | MET (0.69) | JAK2METINPPL1 | |
| SCHEMBL30453123 | 0.79 | JAK2 (0.88) | JAK2MET | |
| SCHEMBL488360 | 0.79 | JAK2 (0.88) | JAK2MET | |
| SCHEMBL488269 | 0.74 | MET (1.00) | JAK2MET | |
| SCHEMBL13412106 | 0.74 | JAK2 (0.62) | JAK2METINPPL1 | |
| SCHEMBL30453779 | 0.74 | MET (1.00) | JAK2MET | |
| SCHEMBL5255394 | 0.74 | JAK2 (0.79) | JAK2METINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |