Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 5/20 | 0.48 |
| ▸ | LDHB | P07195 | 5/20 | 0.48 |
| ▸ | ATR | Q13535 | 6/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487989 | 1.00 | LDHA (0.48) | LDHALDHBATRMAP4K4CSF1R | |
| SCHEMBL5487386 | 0.92 | ATR (0.47) | LDHALDHBATRCSF1RMET | |
| SCHEMBL30454721 | 0.89 | CSF1R (0.45) | LDHALDHBATRMAP4K4CSF1R | |
| SCHEMBL488449 | 0.89 | CSF1R (0.45) | LDHALDHBATRMAP4K4CSF1R | |
| SCHEMBL5487393 | 0.86 | CSF1R (0.48) | ATRMAP4K4CSF1RMET | |
| SCHEMBL488822 | 0.84 | ATR (0.53) | ATRCSF1RMET | |
| SCHEMBL30452937 | 0.84 | ATR (0.53) | ATRCSF1RMET | |
| SCHEMBL488121 | 0.83 | MAP4K4 (0.54) | LDHALDHBMAP4K4METMRGPRX4 | |
| SCHEMBL30453459 | 0.83 | MAP4K4 (0.54) | LDHALDHBMAP4K4METMRGPRX4 | |
| SCHEMBL5484072 | 0.82 | CSF1R (0.45) | ATRMAP4K4CSF1RMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |