Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 9/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488069 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAANPC1GLA | |
| SCHEMBL30454688 | 0.84 | MET (0.49) | ALDH1A1KDM4EGAANPC1GLA | |
| SCHEMBL487709 | 0.84 | MET (0.49) | ALDH1A1KDM4EGAANPC1GLA | |
| SCHEMBL10215491 | 0.82 | MET (0.52) | ALDH1A1KDM4EGAANPC1GLA | |
| SCHEMBL488176 | 0.82 | MET (0.52) | ALDH1A1KDM4EGAANPC1GLA | |
| SCHEMBL30452564 | 0.82 | MET (0.52) | ALDH1A1KDM4EGAANPC1GLA | |
| SCHEMBL30453201 | 0.81 | MAP4K4 (0.64) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL487982 | 0.81 | MAP4K4 (0.64) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL487713 | 0.81 | MET (0.53) | METJAK2MAP4K3MAP4K4IKBKE | |
| SCHEMBL30452521 | 0.81 | MET (0.53) | METJAK2MAP4K3MAP4K4IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |