Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11475129 | 1.00 | MAOB (0.44) | MAOBCHRNB2CHRNA4MAPTCYP3A4 | |
| SCHEMBL11477909 | 0.79 | NR1I2 (0.50) | CHRNB2CHRNA4MAPTLMNAPOLB | |
| SCHEMBL7394763 | 0.78 | S1PR4 (0.46) | MAOBMAPTCYP3A4CYP2A6HPGD | |
| SCHEMBL11479292 | 0.78 | LTA4H (0.54) | MAOBMAPTCYP3A4CYP2A6POLB | |
| SCHEMBL3645477 | 0.78 | CHRNB2 (0.45) | MAOBCHRNB2CHRNA4MAPTCYP3A4 | |
| SCHEMBL11755567 | 0.76 | CHRNB2 (0.46) | CHRNB2CHRNA4MAPTLMNAPOLB | |
| SCHEMBL5981851 | 0.76 | MAPT (0.50) | MAOBMAPTCYP3A4CYP2A6HPGD | |
| SCHEMBL30663731 | 0.75 | MAPT (0.56) | MAOBMAPTCYP3A4CYP2A6HPGD | |
| SCHEMBL10347560 | 0.75 | MAPT (0.56) | MAOBMAPTCYP3A4CYP2A6HPGD | |
| SCHEMBL2487083 | 0.75 | RAB9A (0.56) | MAPTCYP3A4LMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |