Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488229 | 1.00 | MET (0.86) | METKDM4EALDH1A1TSHRTP53 | |
| SCHEMBL487596 | 0.93 | MET (1.00) | METKDM4EALDH1A1TSHRTP53 | |
| SCHEMBL30454825 | 0.84 | MET (0.65) | METKDM4EALDH1A1TSHRTP53 | |
| SCHEMBL487852 | 0.84 | MET (0.65) | METKDM4EALDH1A1TSHRTP53 | |
| SCHEMBL488949 | 0.81 | MET (0.61) | METKDM4EALDH1A1TSHRTP53 | |
| SCHEMBL487711 | 0.81 | MET (0.80) | METKDM4EALDH1A1KDRALK | |
| SCHEMBL487598 | 0.79 | MET (0.76) | METKDM4EALDH1A1KDRALK | |
| SCHEMBL488061 | 0.78 | MET (0.67) | METMEN1MAPTKMT2AMAP4K4 | |
| SCHEMBL30454973 | 0.78 | MET (0.67) | METMEN1MAPTKMT2AMAP4K4 | |
| SCHEMBL488422 | 0.78 | MET (0.61) | METKDM4EMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |