Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.65 |
| ▸ | CSF1R | P07333 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487852 | 1.00 | MET (0.65) | METCSF1RACHEKDM4EALDH1A1 | |
| SCHEMBL30454537 | 0.91 | MET (0.70) | METCSF1RACHEKDM4EALDH1A1 | |
| SCHEMBL488104 | 0.91 | MET (0.70) | METCSF1RACHEKDM4EALDH1A1 | |
| SCHEMBL30453737 | 0.84 | MET (0.86) | METACHEKDM4EALDH1A1TP53 | |
| SCHEMBL488229 | 0.84 | MET (0.86) | METACHEKDM4EALDH1A1TP53 | |
| SCHEMBL27650267 | 0.81 | CSF1R (0.56) | METCSF1RKDM4EALDH1A1 | |
| SCHEMBL488949 | 0.79 | MET (0.61) | METACHEKDM4EALDH1A1TP53 | |
| SCHEMBL487596 | 0.79 | MET (1.00) | METACHEKDM4EALDH1A1TP53 | |
| SCHEMBL27630240 | 0.76 | MET (0.49) | METACHEKDM4EALDH1A1TP53 | |
| SCHEMBL3822499 | 0.75 | PIK3CD (0.52) | METACHEKDM4ETP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |