Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555492 | 1.00 | TYR (0.48) | TYRKDM4EALDH1A3ALDH1A1L3MBTL1 | |
| SCHEMBL15330759 | 0.84 | TYR (0.41) | TYRKDM4EALDH1A3ALDH1A1L3MBTL1 | |
| SCHEMBL2558733 | 0.84 | TYR (0.41) | TYRKDM4EALDH1A3ALDH1A1L3MBTL1 | |
| SCHEMBL15329927 | 0.81 | TYR (0.38) | TYRKDM4EALDH1A3ALDH1A1L3MBTL1 | |
| SCHEMBL2558532 | 0.81 | TYR (0.38) | TYRKDM4EALDH1A3ALDH1A1L3MBTL1 | |
| SCHEMBL29900333 | 0.79 | ALDH1A1 (0.42) | TYRKDM4EALDH1A3ALDH1A1L3MBTL1 | |
| SCHEMBL3231297 | 0.79 | ALDH1A1 (0.40) | TYRALDH1A1CHRNA7LMNA | |
| SCHEMBL475367 | 0.79 | ALDH1A1 (0.42) | TYRKDM4EALDH1A3ALDH1A1L3MBTL1 | |
| SCHEMBL20247172 | 0.79 | KDM4E (0.42) | TYRKDM4EALDH1A3ALDH1A1L3MBTL1 | |
| SCHEMBL890254 | 0.78 | LMNA (0.36) | TYRKDM4EALDH1A1L3MBTL1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |