Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488033 | 1.00 | MET (0.46) | METJAK2MAP4K3NPC1HTT | |
| SCHEMBL487679 | 0.86 | MET (0.57) | METJAK2MAP4K3MAP4K4ALK | |
| SCHEMBL488238 | 0.83 | MET (0.66) | METMAP4K3NPC1HTTPPP1CA | |
| SCHEMBL30453970 | 0.83 | MET (0.66) | METMAP4K3NPC1HTTPPP1CA | |
| SCHEMBL488295 | 0.82 | MET (0.52) | METJAK2MAP4K3MAP4K4ALK | |
| SCHEMBL30452799 | 0.82 | MET (0.52) | METJAK2MAP4K3MAP4K4ALK | |
| SCHEMBL487842 | 0.82 | JAK2 (0.60) | METJAK2MAP4K3CHEK2 | |
| SCHEMBL30453168 | 0.82 | JAK2 (0.60) | METJAK2MAP4K3CHEK2 | |
| SCHEMBL488281 | 0.81 | MAP4K3 (0.49) | METMAP4K3NPC1HTTSMN1; SMN2 | |
| SCHEMBL30454994 | 0.81 | MAP4K3 (0.49) | METMAP4K3NPC1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |