Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 5/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488281 | 1.00 | MAP4K3 (0.49) | MAP4K3MAP4K4NPC1RAB9AMAPT | |
| SCHEMBL30453851 | 0.90 | MAP4K4 (0.60) | MAP4K3MAP4K4NPC1RAB9ALTA4H | |
| SCHEMBL488264 | 0.90 | MAP4K4 (0.60) | MAP4K3MAP4K4NPC1RAB9ALTA4H | |
| SCHEMBL488238 | 0.82 | MET (0.66) | MAP4K3MAP4K4NPC1RAB9AMAPT | |
| SCHEMBL30453970 | 0.82 | MET (0.66) | MAP4K3MAP4K4NPC1RAB9AMAPT | |
| SCHEMBL488849 | 0.82 | MAP4K3 (0.53) | MAP4K3MAP4K4NPC1RAB9AMAPT | |
| SCHEMBL30453451 | 0.82 | MAP4K3 (0.53) | MAP4K3MAP4K4NPC1RAB9AMAPT | |
| SCHEMBL30453706 | 0.81 | MET (0.46) | MAP4K3MAP4K4NPC1METHTT | |
| SCHEMBL488033 | 0.81 | MET (0.46) | MAP4K3MAP4K4NPC1METHTT | |
| SCHEMBL30453298 | 0.80 | MAP4K3 (0.52) | MAP4K3MAP4K4NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |