Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 9/20 | 0.47 |
| ▸ | QDPR | P09417 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341889 | 0.81 | HTR2C (0.51) | SIGMAR1HTR2CQDPRPIM1PIM3 | |
| SCHEMBL30454060 | 0.81 | HTR2C (0.51) | SIGMAR1HTR2CQDPRPIM1PIM3 | |
| SCHEMBL171110 | 0.80 | SIGMAR1 (0.49) | SIGMAR1HTR2CQDPRPIM1PIM3 | |
| SCHEMBL171596 | 0.80 | PIM1 (0.51) | SIGMAR1HTR2CQDPRPIM1PIM3 | |
| SCHEMBL7940586 | 0.80 | SIGMAR1 (0.49) | SIGMAR1HTR2CQDPRPIM1PIM3 | |
| SCHEMBL14761633 | 0.80 | CDK9 (0.57) | SIGMAR1HTR2CQDPRPIM1PIM3 | |
| SCHEMBL3453255 | 0.80 | HTR2C (0.51) | SIGMAR1HTR2CQDPRPIM1PIM3 | |
| Hydrochloric Acid SCHEMBL4588150 | 0.79 | HTR2C (0.53) | SIGMAR1HTR2CQDPRPIM1PIM3 | |
| SCHEMBL169395 | 0.79 | SIGMAR1 (0.66) | SIGMAR1HTR2CQDPRKDM4EALDH1A1 | |
| SCHEMBL3453676 | 0.76 | HTR2C (0.51) | SIGMAR1HTR2CQDPRPIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029947-A1 | Pyridyltetrahydropyridines and Pyridylpiperidines, and Method of Manufacturing Them | FUJIFILM FINECHEMICALS CO., LTD | 2010-02-04 | — | — | US | disclosed |
| US-7632950-B2 | Pyridyltetrahydropyridines and pyridylpiperidines and method of manufacturing them | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2009-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029947-A1 | Pyridyltetrahydropyridines and Pyridylpiperidines, and Method of Manufacturing Them | QDPR, HRH4, HRH2 | SIGMAR1 1466/4885HTR2C 399/4885QDPR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.