Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12255485 | 0.89 | SLC6A4 (0.50) | KDM1AMAOAMAOBTRPV6 | |
| SCHEMBL21608358 | 0.83 | EED (0.45) | KDM1AMAOAMAOB | |
| SCHEMBL22371834 | 0.79 | GPR183 (0.44) | — | |
| SCHEMBL20857050 | 0.78 | TRPV6 (0.38) | KDM1AMAOAMAOBGRM2TRPV6 | |
| SCHEMBL22387770 | 0.77 | GPR119 (0.56) | — | |
| SCHEMBL1967486 | 0.77 | ADRA1D (0.44) | KDM1AMAOAMAOBTRPV6ACACB | |
| SCHEMBL30837844 | 0.76 | KDM1A (0.41) | KDM1AMAOAMAOBTRPV6NAAA | |
| SCHEMBL12147777 | 0.76 | PDE10A (0.40) | — | |
| SCHEMBL31508335 | 0.76 | CYP11B1 (0.41) | GRM2TRPV6 | |
| SCHEMBL91410 | 0.75 | KDM1A (0.44) | KDM1AMAOAMAOBNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4196220-A1 | TRIAZOLE-PYRIDINYL SUBSTITUTED AZACYCLOHEXYL ACETIC ACID COMPOUNDS AS LPA RECEPTOR ANTAGONISTS | Viva Star Biosciences Limited (HK) | 2023-06-21 | — | — | EP | disclosed |