Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25356919 | 1.00 | HSD17B10 (0.36) | HSD17B10TSHRALOX15PKMPDE4D | |
| SCHEMBL25356115 | 0.85 | TSHR (0.38) | HSD17B10TSHRPOLBSMN1; SMN2PTPN1 | |
| SCHEMBL30453142 | 0.85 | TSHR (0.38) | HSD17B10TSHRPOLBSMN1; SMN2PTPN1 | |
| SCHEMBL30454331 | 0.84 | — | — | |
| SCHEMBL25354537 | 0.84 | — | — | |
| SCHEMBL25353387 | 0.76 | CA2 (0.43) | HSD17B10TSHRALOX15 | |
| SCHEMBL5037861 | 0.66 | TAAR1 (0.47) | POLBLMNA | |
| SCHEMBL25356082 | 0.65 | PKM (0.40) | ALOX15PKMTHRBTHRA | |
| SCHEMBL25354521 | 0.64 | CA2 (0.33) | — | |
| SCHEMBL11563914 | 0.63 | PKM (0.47) | HSD17B10TSHRALOX15PKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |