Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25356115 | 1.00 | TSHR (0.38) | TSHRALDH1A1CYP1A2CYP2C19POLB | |
| SCHEMBL30454209 | 0.85 | HSD17B10 (0.36) | TSHRALDH1A1POLBSMN1; SMN2HSD17B10 | |
| SCHEMBL25356919 | 0.85 | HSD17B10 (0.36) | TSHRALDH1A1POLBSMN1; SMN2HSD17B10 | |
| SCHEMBL25354537 | 0.82 | — | — | |
| SCHEMBL30454331 | 0.82 | — | — | |
| SCHEMBL25353387 | 0.72 | CA2 (0.43) | TSHRHSD17B10 | |
| SCHEMBL11559970 | 0.69 | KDM4E (0.51) | TSHRALDH1A1CYP1A2CYP2C19POLB | |
| SCHEMBL15699612 | 0.65 | TSHR (0.39) | TSHRALDH1A1CYP1A2CYP2C19POLB | |
| SCHEMBL30280664 | 0.65 | PKM (0.41) | TSHRALDH1A1CYP1A2CYP2C19POLB | |
| SCHEMBL16784831 | 0.63 | ALDH1A1 (0.57) | TSHRALDH1A1CYP1A2CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |