Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.60 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.60 |
| ▸ | HPGDS | O60760 | 2/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.50 |
| ▸ | ATR | Q13535 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488149 | 1.00 | MET (0.60) | METCHEK2HPGDSCD274ATR | |
| SCHEMBL488889 | 0.93 | MAP4K4 (0.54) | METCHEK2HPGDSATRMAP4K4 | |
| SCHEMBL30454081 | 0.93 | MAP4K4 (0.54) | METCHEK2HPGDSATRMAP4K4 | |
| SCHEMBL30453897 | 0.93 | MET (0.65) | METCHEK2ATRALDH1A1MAP4K4 | |
| SCHEMBL488319 | 0.93 | MET (0.65) | METCHEK2ATRALDH1A1MAP4K4 | |
| SCHEMBL30454806 | 0.90 | MET (0.66) | METCHEK2HPGDSCD274ALDH1A1 | |
| SCHEMBL488802 | 0.90 | MET (0.66) | METCHEK2HPGDSCD274ALDH1A1 | |
| SCHEMBL488168 | 0.90 | MET (0.59) | METCHEK2HPGDSCD274ATR | |
| SCHEMBL488600 | 0.89 | MET (0.59) | METCHEK2HPGDSCD274ATR | |
| SCHEMBL30454107 | 0.89 | MET (0.59) | METCHEK2HPGDSCD274ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |