Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.65 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.65 |
| ▸ | ATR | Q13535 | 6/20 | 0.57 |
| ▸ | CSF1R | P07333 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.42 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488319 | 1.00 | MET (0.65) | METCHEK2ATRCSF1RALDH1A1 | |
| SCHEMBL30453082 | 0.95 | MET (0.63) | METCHEK2ATRCSF1R | |
| SCHEMBL487993 | 0.95 | MET (0.63) | METCHEK2ATRCSF1R | |
| SCHEMBL30454540 | 0.93 | MET (0.60) | METCHEK2ATRALDH1A1MAP4K4 | |
| SCHEMBL488149 | 0.93 | MET (0.60) | METCHEK2ATRALDH1A1MAP4K4 | |
| SCHEMBL30453791 | 0.93 | ATR (0.59) | METCHEK2ATRIKBKBMAP4K4 | |
| SCHEMBL488359 | 0.93 | ATR (0.59) | METCHEK2ATRIKBKBMAP4K4 | |
| SCHEMBL488168 | 0.92 | MET (0.59) | METCHEK2ATRCSF1RBMPR1B | |
| SCHEMBL488699 | 0.88 | MET (0.55) | METCHEK2ATRIKBKBMAP4K4 | |
| SCHEMBL30452733 | 0.88 | MET (0.55) | METCHEK2ATRIKBKBMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |