Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487791 | 1.00 | MET (0.70) | METNPC1RAB9APRKAB1KDR | |
| SCHEMBL487711 | 0.83 | MET (0.80) | METNPC1RAB9APRKAB1KDR | |
| SCHEMBL487596 | 0.83 | MET (1.00) | METNPC1RAB9APRKAB1KDR | |
| SCHEMBL488559 | 0.78 | MET (0.67) | METNPC1RAB9APRKAB1KDR | |
| SCHEMBL487977 | 0.78 | MET (0.66) | METNPC1RAB9APRKAB1KDR | |
| SCHEMBL487598 | 0.77 | MET (0.76) | METNPC1RAB9APRKAB1KDR | |
| SCHEMBL488770 | 0.75 | MET (0.63) | METNPC1RAB9APRKAB1KDR | |
| SCHEMBL488229 | 0.75 | MET (0.86) | METNPC1RAB9AKDRACHE | |
| SCHEMBL30453737 | 0.75 | MET (0.86) | METNPC1RAB9AKDRACHE | |
| SCHEMBL7140786 | 0.72 | LTA4H (0.62) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |