Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768874 | 1.00 | ACP1 (0.46) | ACP1CYP1A2TSHRTDP1CYP3A4 | |
| SCHEMBL6735075 | 0.82 | MAPT (0.38) | ACP1CYP1A2TSHRTDP1CYP3A4 | |
| SCHEMBL22651898 | 0.80 | RORC (0.38) | ACP1CYP1A2TSHRTDP1CYP3A4 | |
| SCHEMBL8979233 | 0.79 | ALDH1A1 (0.38) | ACP1CYP1A2TSHRTDP1CYP3A4 | |
| SCHEMBL5539229 | 0.79 | ESR1 (0.39) | ACP1CYP1A2TSHRTDP1CYP3A4 | |
| SCHEMBL17479870 | 0.79 | HDAC6 (0.45) | ACP1CYP1A2TSHRTDP1CYP3A4 | |
| SCHEMBL28122138 | 0.79 | ESR1 (0.39) | ACP1CYP1A2TSHRTDP1CYP3A4 | |
| SCHEMBL1201242 | 0.78 | ALDH1A1 (0.46) | ACP1TSHRTDP1MAPK1CLK4 | |
| SCHEMBL29987688 | 0.78 | ALDH1A1 (0.46) | ACP1TSHRTDP1MAPK1CLK4 | |
| SCHEMBL2093130 | 0.77 | ESR1 (0.38) | ACP1CYP1A2TSHRTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386257-B | Process for preparing enzalutamide using novel intermediates | 阿尔第药物实验室有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-111386257-B | Process for preparing enzalutamide using novel intermediates | 阿尔第药物实验室有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-3717457-B1 | PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE | AARTI INDUSTRIES LTD (IN) | 2023-06-21 | — | — | EP | disclosed |