SCHEMBL5539229

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5539629	0.85	ESR1 (0.40)	ESR1POLQRORCIDO1ACP1
	SCHEMBL5542515	0.82	ESR1 (0.39)	ESR1POLQRORCIDO1ACP1
	SCHEMBL30454780	0.79	ACP1 (0.46)	ESR1POLQRORCIDO1ACP1
	SCHEMBL1768874	0.79	ACP1 (0.46)	ESR1POLQRORCIDO1ACP1
	SCHEMBL9229560	0.76	ESR1 (0.46)	ESR1POLQTDP1HDAC6HSD11B1
	SCHEMBL5546043	0.75	TAAR1 (0.39)	ESR1CYP1A2CYP2C19CYP2D6ALDH1A1
	SCHEMBL5540772	0.74	SLC6A3 (0.41)	ALDH1A1POLBL3MBTL1HSD11B1
	SCHEMBL9821084	0.73	ALDH1A1 (0.44)	ESR1POLQRORCIDO1ALDH1A1
	SCHEMBL22651898	0.73	RORC (0.38)	ESR1POLQRORCIDO1ACP1
	SCHEMBL2754134	0.73	POLQ (0.43)	ESR1POLQALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.