Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.70 |
| ▸ | CSF1R | P07333 | 3/20 | 0.58 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488104 | 1.00 | MET (0.70) | METCSF1RACHEBCHEMAOA | |
| SCHEMBL487852 | 0.91 | MET (0.65) | METCSF1RACHEBCHEMAOA | |
| SCHEMBL30454825 | 0.91 | MET (0.65) | METCSF1RACHEBCHEMAOA | |
| SCHEMBL27650267 | 0.86 | CSF1R (0.56) | METCSF1RKDM4EALDH1A1 | |
| SCHEMBL487596 | 0.82 | MET (1.00) | METACHEBCHEMAOAMAOB | |
| SCHEMBL27630100 | 0.81 | MET (0.60) | METACHEBCHEMAOAMAOB | |
| SCHEMBL488652 | 0.77 | CSF1R (0.67) | METCSF1RRAB9AKDM4E | |
| SCHEMBL30454422 | 0.77 | CSF1R (0.67) | METCSF1RRAB9AKDM4E | |
| SCHEMBL30453737 | 0.77 | MET (0.86) | METACHENPC1RAB9AADORA2A | |
| SCHEMBL488229 | 0.77 | MET (0.86) | METACHENPC1RAB9AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |