Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454449 | 0.92 | KDM4E (0.49) | HSD17B10KDM4ELMNATRPV1POLB | |
| SCHEMBL30455167 | 0.84 | HSD17B10 (0.48) | HSD17B10KDM4ELMNATRPV1POLB | |
| SCHEMBL30594962 | 0.81 | NPC1 (0.41) | HSD17B10KDM4ELMNAPOLBAMY1A | |
| SCHEMBL30594977 | 0.80 | POLB (0.42) | HSD17B10KDM4ELMNAPOLBAMY1A | |
| SCHEMBL30455110 | 0.80 | AMY1A (0.39) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL30455089 | 0.79 | AMY1A (0.39) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL30455313 | 0.77 | TRPV1 (0.47) | HSD17B10KDM4ELMNATRPV1POLB | |
| SCHEMBL29002513 | 0.77 | TRPV1 (0.47) | HSD17B10KDM4ELMNATRPV1POLB | |
| SCHEMBL29002507 | 0.74 | HSD17B10 (0.46) | HSD17B10KDM4ELMNATRPV1POLB | |
| SCHEMBL30455646 | 0.72 | RXFP1 (0.40) | HSD17B10KDM4ELMNAPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |