Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051477 | 1.00 | HCRTR1 (0.58) | HCRTR1L3MBTL1GLAMAPTGAA | |
| SCHEMBL5052356 | 0.86 | LMNA (0.53) | L3MBTL1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3029800 | 0.85 | HCRTR1 (0.62) | HCRTR1L3MBTL1GLAMAPTGAA | |
| SCHEMBL11763044 | 0.85 | HCRTR1 (0.66) | HCRTR1L3MBTL1GLAMAPTGAA | |
| SCHEMBL5055118 | 0.85 | LMNA (0.59) | L3MBTL1MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL1998630 | 0.84 | ABCB1 (0.67) | MAPTMAPK1NPSR1LMNAALDH1A1 | |
| SCHEMBL1448831 | 0.84 | HCRTR1 (0.60) | HCRTR1L3MBTL1GLAMAPTGAA | |
| SCHEMBL11461787 | 0.82 | LMNA (0.68) | L3MBTL1MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL15766880 | 0.82 | LMNA (0.68) | L3MBTL1MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL11259348 | 0.82 | LMNA (0.68) | L3MBTL1MAPTMAPK1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810143-B1 | NADPH OXIDASE INHIBITORS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND APPLICATION THEREOF | TAIWANJ PHARMACEUTICALS CO LTD (TW) | 2025-04-16 | — | — | EP | disclosed |
| US-11661400-B2 | NADPH oxidase inhibitors, pharmaceutical composition comprising the same, and application thereof | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2023-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661400-B2 | NADPH oxidase inhibitors, pharmaceutical composition comprising the same, and application thereof | NOX1, CYBB, NOX4 | HCRTR1 1735/4885L3MBTL1 4867/4885GLA 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.