Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | PDE5A | O76074 | 2/20 | 0.59 |
| ▸ | USP1 | O94782 | 1/20 | 0.56 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455311 | 0.83 | MAPT (0.81) | MAPTNPSR1MAPK1KDM4EPDE5A | |
| SCHEMBL22342962 | 0.81 | CTNNB1 (0.77) | MAPTNPSR1MAPK1KDM4EPDE5A | |
| SCHEMBL29490089 | 0.81 | CTNNB1 (0.77) | MAPTNPSR1MAPK1KDM4EPDE5A | |
| SCHEMBL3114782 | 0.79 | PDE5A (0.67) | MAPTNPSR1MAPK1KDM4EPDE5A | |
| SCHEMBL13192094 | 0.79 | PDE5A (0.67) | MAPTNPSR1MAPK1PDE5AUSP1 | |
| SCHEMBL14256686 | 0.79 | PDE5A (0.55) | MAPTNPSR1MAPK1KDM4EPDE5A | |
| SCHEMBL30455233 | 0.78 | MEN1 (0.58) | MAPTNPSR1MAPK1KDM4EPDE5A | |
| SCHEMBL30455471 | 0.78 | MAPT (0.72) | MAPTNPSR1MAPK1KDM4EPDE5A | |
| SCHEMBL22343385 | 0.78 | KMT2A (0.67) | MAPTNPSR1MAPK1KDM4EKMT2A | |
| SCHEMBL29490079 | 0.78 | KMT2A (0.67) | MAPTNPSR1MAPK1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051290-A1 | NOVEL COMPOUND FOR IMPROVING SLEEP OR USE THEREOF | UNIV AJOU IND ACADEMIC COOP FOUND (KR) | 2025-02-13 | — | — | US | disclosed |
| WO-2023121429-A1 | NOVEL COMPOUND FOR IMPROVING SLEEP OR USE THEREOF | 아주대학교산학협력단 | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051290-A1 | NOVEL COMPOUND FOR IMPROVING SLEEP OR USE THEREOF | ADORA2A, HCRTR1, ADORA1 | MAPT 4331/4885NPSR1 46/4885MAPK1 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.