SCHEMBL30455233

SCHEMBL30455233

CC(Nc1nc(NCc2ccc3c(c2)OCO3)nc2ccccc12)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.58
KMT2A Q03164 7/20 0.58
PDE5A O76074 1/20 0.57
MAPT P10636 3/20 0.53
NPSR1 Q6W5P4 1/20 0.53
USP1 O94782 1/20 0.52
WDR48 Q8TAF3 1/20 0.52
LMNA P02545 4/20 0.52
MAPK1 P28482 4/20 0.52
ALDH1A1 P00352 3/20 0.52
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP2C19 P33261 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TP53 P04637 2/20 0.52
HIF1A Q16665 1/20 0.52
BCHE P06276 2/20 0.51
ACHE P22303 2/20 0.51
APP P05067 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30454922 0.78 MAPT (0.59) MEN1KMT2APDE5AMAPTNPSR1
SCHEMBL30455125 0.78 LMNA (0.60) MEN1KMT2APDE5AMAPTNPSR1
SCHEMBL30456191 0.77 APP (0.60) MEN1KMT2AMAPTNPSR1LMNA
SCHEMBL13192094 0.76 PDE5A (0.67) MEN1KMT2APDE5AMAPTNPSR1
SCHEMBL3114782 0.76 PDE5A (0.67) MEN1KMT2APDE5AMAPTNPSR1
SCHEMBL3681166 0.76 MEN1 (0.97) MEN1KMT2AALDH1A1CYP2D6TSHR
SCHEMBL14256686 0.75 PDE5A (0.55) MEN1KMT2APDE5AMAPTNPSR1
SCHEMBL30455166 0.75 MAPT (0.60) MEN1KMT2APDE5AMAPTNPSR1
SCHEMBL25251389 0.74 MRGPRX1 (0.56) MEN1KMT2APDE5AMAPTNPSR1
SCHEMBL28929875 0.74 MEN1 (0.74) MEN1KMT2AMAPTALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051290-A1 NOVEL COMPOUND FOR IMPROVING SLEEP OR USE THEREOF UNIV AJOU IND ACADEMIC COOP FOUND (KR) 2025-02-13 US disclosed
WO-2023121429-A1 NOVEL COMPOUND FOR IMPROVING SLEEP OR USE THEREOF 아주대학교산학협력단 2023-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051290-A1 NOVEL COMPOUND FOR IMPROVING SLEEP OR USE THEREOF ADORA2A, HCRTR1, ADORA1 MEN1 4612/4885KMT2A 568/4885PDE5A 272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.