Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454430 | 1.00 | GLP1R (0.34) | GLP1RKCNH2DRD2HTR2AHTR2C | |
| SCHEMBL30454533 | 0.80 | GLP1R (0.37) | GLP1RKCNH2DRD2HTR2AHTR2C | |
| SCHEMBL30453892 | 0.77 | C5AR1 (0.40) | — | |
| SCHEMBL22664508 | 0.74 | GLP1R (0.65) | GLP1R | |
| SCHEMBL22391654 | 0.74 | GLP1R (0.65) | GLP1R | |
| SCHEMBL22392142 | 0.74 | HTR1A (0.40) | DRD2HTR2AHTR2CHTR6HTR1A | |
| SCHEMBL30454719 | 0.74 | HTR1A (0.40) | DRD2HTR2AHTR2CHTR6HTR1A | |
| SCHEMBL22392141 | 0.73 | GLP1R (0.56) | GLP1R | |
| SCHEMBL22392140 | 0.73 | GLP1R (0.56) | GLP1R | |
| SCHEMBL22391591 | 0.71 | VEGFA (0.44) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |