Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 7/20 | 0.40 |
| ▸ | HTR3A | P46098 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.39 |
| ▸ | HTR3B | O95264 | 2/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22392142 | 1.00 | HTR1A (0.40) | HTR1AHTR2CHTR2ADRD2DRD3 | |
| SCHEMBL22391591 | 0.80 | VEGFA (0.44) | CYP3A4HTT | |
| SCHEMBL30454430 | 0.74 | GLP1R (0.34) | HTR1AHTR2CHTR2ADRD2DRD4 | |
| SCHEMBL30455093 | 0.74 | GLP1R (0.34) | HTR1AHTR2CHTR2ADRD2DRD4 | |
| SCHEMBL30455284 | 0.73 | ALDH1A1 (0.37) | CYP3A4SLC6A4HTTSLC6A2 | |
| SCHEMBL22391775 | 0.72 | HTR2C (0.52) | HTR2CHTR2AHTR3AHTR3EHTR3B | |
| SCHEMBL30454467 | 0.72 | HTR2C (0.52) | HTR2CHTR2AHTR3AHTR3EHTR3B | |
| SCHEMBL29772851 | 0.70 | HTR3A (0.55) | HTR1AHTR2CHTR2ADRD2DRD3 | |
| SCHEMBL234944 | 0.70 | HTR3A (0.55) | HTR1AHTR2CHTR2ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL22533692 | 0.68 | HTR3A (0.54) | HTR1AHTR2CHTR2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |