Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP11 | Q9NR21 | 8/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25248465 | 1.00 | PARP11 (0.53) | PARP11PARP10PIM1PIM2GRM5 | |
| SCHEMBL25245298 | 0.93 | PARP10 (0.42) | PARP11PARP10PIM1PIM2TUBB4A | |
| SCHEMBL30455485 | 0.93 | PARP10 (0.42) | PARP11PARP10PIM1PIM2TUBB4A | |
| SCHEMBL30455449 | 0.91 | TARS1 (0.42) | PARP11PARP10PIM1PIM2GRM5 | |
| SCHEMBL25253418 | 0.91 | TARS1 (0.42) | PARP11PARP10PIM1PIM2GRM5 | |
| SCHEMBL25246903 | 0.85 | CLK4 (0.51) | PIM1PIM2GSK3BEGFR | |
| SCHEMBL30455490 | 0.85 | CLK4 (0.51) | PIM1PIM2GSK3BEGFR | |
| SCHEMBL25246086 | 0.81 | OPRD1 (0.41) | EGFROPRD1 | |
| SCHEMBL30455408 | 0.81 | OPRD1 (0.41) | EGFROPRD1 | |
| SCHEMBL25784742 | 0.80 | PARP11 (0.53) | PARP11PARP10GRM5TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | claimed |
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |