Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARS1 | P26639 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PRF1 | P14222 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455449 | 1.00 | TARS1 (0.42) | TARS1CLK4DYRK1BTYRO3NTRK2 | |
| SCHEMBL25246903 | 0.92 | CLK4 (0.51) | TARS1CLK4DYRK1BTYRO3NTRK2 | |
| SCHEMBL30455490 | 0.92 | CLK4 (0.51) | TARS1CLK4DYRK1BTYRO3NTRK2 | |
| SCHEMBL30455553 | 0.91 | PARP11 (0.53) | PIM1GSK3BPARP10PARP11EGFR | |
| SCHEMBL25248465 | 0.91 | PARP11 (0.53) | PIM1GSK3BPARP10PARP11EGFR | |
| SCHEMBL25247709 | 0.86 | ROCK2 (0.34) | CLK4DYRK1BTYRO3NTRK2PIM1 | |
| SCHEMBL30456104 | 0.86 | ROCK2 (0.34) | CLK4DYRK1BTYRO3NTRK2PIM1 | |
| SCHEMBL25245298 | 0.85 | PARP10 (0.42) | CLK4DYRK1BTYRO3NTRK2PIM1 | |
| SCHEMBL30455485 | 0.85 | PARP10 (0.42) | CLK4DYRK1BTYRO3NTRK2PIM1 | |
| SCHEMBL25246086 | 0.83 | OPRD1 (0.41) | EGFRPRF1PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | claimed |
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |