Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.51 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | MST1R | Q04912 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25246903 | 1.00 | CLK4 (0.51) | CLK4DYRK1BNTRK2TYRO3FYN | |
| SCHEMBL25253418 | 0.92 | TARS1 (0.42) | CLK4DYRK1BNTRK2TYRO3FYN | |
| SCHEMBL30455449 | 0.92 | TARS1 (0.42) | CLK4DYRK1BNTRK2TYRO3FYN | |
| SCHEMBL30455485 | 0.91 | PARP10 (0.42) | CLK4DYRK1BNTRK2TYRO3EGFR | |
| SCHEMBL25245298 | 0.91 | PARP10 (0.42) | CLK4DYRK1BNTRK2TYRO3EGFR | |
| SCHEMBL25248465 | 0.85 | PARP11 (0.53) | GSK3BEGFRPIM1PIM2 | |
| SCHEMBL30455553 | 0.85 | PARP11 (0.53) | GSK3BEGFRPIM1PIM2 | |
| SCHEMBL25249612 | 0.85 | SDCBP (0.41) | EGFRMEN1KMT2APLA2G7KDM4E | |
| SCHEMBL30455455 | 0.85 | SDCBP (0.41) | EGFRMEN1KMT2APLA2G7KDM4E | |
| SCHEMBL25247709 | 0.84 | ROCK2 (0.34) | CLK4DYRK1BNTRK2TYRO3NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | claimed |
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |