Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26349182 | 1.00 | MGMT (0.39) | MGMTMGLLCA12CA1CA2 | |
| SCHEMBL30459733 | 1.00 | MGMT (0.39) | MGMTMGLLCA12CA1CA2 | |
| SCHEMBL25495612 | 0.86 | MGMT (0.42) | MGMTMGLLABCG2 | |
| SCHEMBL17262434 | 0.84 | MGMT (0.40) | MGMTMGLLABCG2 | |
| SCHEMBL30458078 | 0.82 | MGMT (0.42) | MGMTMGLLCA12CA1CA2 | |
| SCHEMBL26349179 | 0.82 | MGMT (0.42) | MGMTMGLLCA12CA1CA2 | |
| SCHEMBL28194378 | 0.82 | MGLL (0.43) | MGLLCA12CA1CA2CA4 | |
| SCHEMBL18212282 | 0.78 | MGMT (0.40) | MGMTMGLLABCG2 | |
| SCHEMBL26349168 | 0.78 | MGMT (0.43) | MGMTMGLLABCG2 | |
| SCHEMBL29199650 | 0.77 | HPGD (0.49) | MGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192468-A2 | HETEROARYL AND HETEROCYCLYL COMPOUNDS | Sigilon Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |