SCHEMBL25495612

SCHEMBL25495612

[N-]=[N+]=NCCOCCOCCOCCOCCN1C(=O)C(Br)=C(Br)C1=O

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MGMT P16455 1/20 0.42
▸ MGLL Q99685 1/20 0.38
▸ ABCG2 Q9UNQ0 6/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17262434 0.98 MGMT (0.40) MGMTMGLLABCG2
SCHEMBL30455579 0.86 MGMT (0.39) MGMTMGLLABCG2
SCHEMBL30459733 0.86 MGMT (0.39) MGMTMGLLABCG2
SCHEMBL26349182 0.86 MGMT (0.39) MGMTMGLLABCG2
SCHEMBL18212282 0.82 MGMT (0.40) MGMTMGLLABCG2
SCHEMBL26349179 0.80 MGMT (0.42) MGMTMGLLABCG2
SCHEMBL26349189 0.80 MGMT (0.42) MGMTMGLL
SCHEMBL30458078 0.80 MGMT (0.42) MGMTMGLLABCG2
SCHEMBL29199650 0.80 HPGD (0.49) MGMT
SCHEMBL25495610 0.79 MGLL (0.67) MGMTMGLLABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117915956-A M6PR cell surface receptor binding compounds and conjugates 利西亚治疗公司 2024-04-19 — — CN disclosed
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 — — US disclosed
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed
EP-4087584-A2 CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2022-11-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R MGMT 2296/4885MGLL 883/4885ABCG2 675/4885
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A MGMT 4124/4885MGLL 508/4885ABCG2 337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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