SCHEMBL30455669

SCHEMBL30455669

CC1(C)CCc2cc(F)c(Cl)cc2O1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.43
PKLR P30613 1/20 0.43
SCN9A Q15858 4/20 0.39
MAPT P10636 2/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 2/20 0.36
SCN5A Q14524 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
KDM1A O60341 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
COXFA4 O00483 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5986967 0.81 PKM (0.41) PKMPKLRMAPTNPC1RAB9A
SCHEMBL23423286 0.78 PKM (0.41) PKMPKLRSCN9AMAPTNPC1
SCHEMBL5308527 0.78 NPC1 (0.43) PKMPKLRMAPTNPC1RAB9A
SCHEMBL3243563 0.77 FTO (0.43) PKMPKLRSCN9AMAPTNPC1
SCHEMBL23422992 0.72 KDM1A (0.40) PKMSCN9AMAPTNPC1RAB9A
SCHEMBL23746308 0.72 HTR2C (0.46) PKMPKLRSCN9AMAPTNPC1
SCHEMBL6025550 0.72 PKM (0.48) PKMPKLRMAPTNPC1RAB9A
SCHEMBL30888534 0.72 MAPT (0.47) PKMPKLRMAPTNPC1RAB9A
SCHEMBL10754154 0.70 MAPT (0.39) PKMPKLRMAPTNPC1RAB9A
SCHEMBL21994829 0.70 AKR1B1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630403-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121129-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed
EP-4156936-A1 ACTIVE COMPOUND COMBINATIONS Bayer Aktiengesellschaft (DE) 2023-04-05 EP disclosed