Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028957 | 1.00 | BCAT2 (0.51) | BCAT2PTPN1LMNAGSK3BHPGDS | |
| SCHEMBL16648462 | 0.84 | PTPN1 (0.47) | PTPN1GSK3BHPGDSCA9CA1 | |
| SCHEMBL7614169 | 0.83 | BCAT2 (0.53) | BCAT2LMNACA9CA1CA2 | |
| SCHEMBL13651738 | 0.83 | BCAT2 (0.53) | BCAT2LMNACA9CA1CA2 | |
| SCHEMBL29709071 | 0.81 | PTPN1 (0.49) | PTPN1GSK3BHPGDSCA9CA1 | |
| SCHEMBL13647215 | 0.80 | BCAT2 (0.50) | BCAT2LMNACA9CA1CA2 | |
| SCHEMBL4321077 | 0.78 | BCAT2 (0.59) | BCAT2LMNACA9CA1CA2 | |
| SCHEMBL7904042 | 0.77 | PTPN1 (0.45) | PTPN1GSK3BHPGDSCA9CA1 | |
| SCHEMBL1988980 | 0.77 | BCAT2 (0.51) | BCAT2LMNACA9CA1CA2 | |
| SCHEMBL1988936 | 0.77 | BCAT2 (0.47) | BCAT2LMNACA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810143-B1 | NADPH OXIDASE INHIBITORS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND APPLICATION THEREOF | TAIWANJ PHARMACEUTICALS CO LTD (TW) | 2025-04-16 | — | — | EP | disclosed |
| US-11661400-B2 | NADPH oxidase inhibitors, pharmaceutical composition comprising the same, and application thereof | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2023-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661400-B2 | NADPH oxidase inhibitors, pharmaceutical composition comprising the same, and application thereof | NOX1, CYBB, NOX4 | BCAT2 2401/4885PTPN1 331/4885LMNA 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.