Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 8/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30090679 | 0.79 | CA1 (0.70) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL29709071 | 0.77 | PTPN1 (0.49) | PTPN1CA1CA2MMP1MMP2 | |
| SCHEMBL30455726 | 0.77 | BCAT2 (0.51) | PTPN1CA1CA2CA9CA12 | |
| SCHEMBL5028957 | 0.77 | BCAT2 (0.51) | PTPN1CA1CA2CA9CA12 | |
| SCHEMBL16648462 | 0.76 | PTPN1 (0.47) | PTPN1CA1CA2CA9CA12 | |
| SCHEMBL9409754 | 0.73 | PTPN1 (0.65) | PTPN1GSK3BALDH1A1HPGDSTSHR | |
| SCHEMBL10722435 | 0.71 | CA1 (0.40) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL38141 | 0.69 | ERCC5 (0.58) | PTPN1GSK3BALDH1A1HPGDSCYP1A2 | |
| SCHEMBL6657858 | 0.69 | ACLY (0.44) | PTPN1CA1CA2MMP1MMP2 | |
| SCHEMBL29621373 | 0.69 | ERCC5 (0.58) | PTPN1GSK3BALDH1A1HPGDSCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |