Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047858 | 0.84 | CA1 (0.54) | SMN1; SMN2NPC1RAB9AMCHR1ALDH1A1 | |
| SCHEMBL13835114 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMCHR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3053759 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AMCHR1ALDH1A1 | |
| SCHEMBL3045531 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMCHR1ALDH1A1 | |
| SCHEMBL13835377 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMCHR1ALDH1A1 | |
| SCHEMBL3049528 | 0.82 | CA2 (0.54) | SMN1; SMN2NPC1RAB9AMCHR1ALDH1A1 | |
| SCHEMBL15103786 | 0.78 | NPC1 (0.46) | SMN1; SMN2NPC1RAB9AMCHR1ALDH1A1 | |
| SCHEMBL3062077 | 0.78 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9AMCHR1ALDH1A1 | |
| SCHEMBL14686155 | 0.78 | CACNA1H (0.48) | — | |
| SCHEMBL3273830 | 0.77 | RAB9A (0.49) | SMN1; SMN2NPC1RAB9AMCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130029991-A1 | New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists | BEKE GYULA (HU) | 2013-01-31 | — | — | US | disclosed |
| US-20120295910-A1 | New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists | BEKE GYULA (HU) | 2012-11-22 | — | — | US | disclosed |
| US-20100105686-A1 | PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295910-A1 | New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists | BDKRB1, BDKRB2, HRH4 | SMN1; SMN2 4333/4885NPC1 2755/4885RAB9A 1432/4885 |
| US-20130029991-A1 | New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists | BDKRB1, BDKRB2, HRH4 | SMN1; SMN2 4307/4885NPC1 2913/4885RAB9A 1379/4885 |
| US-20100105686-A1 | PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | BDKRB1, BDKRB2, HRH1 | SMN1; SMN2 4111/4885NPC1 2998/4885RAB9A 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.